Comparing Phytochemicals and Conventional Antibiotics: Mechanisms, Affinities, and Therapeutic Potential Review

Authors

  • Dr. Surya Narayan Das Prof Cum Principal, Gayatri College of Pharmacy, Sambalpur, INDIA.
  • Akshya Kumar Mishra Associate Prof, Department of Microbiology, BKCP, Nuapada, INDIA.

DOI:

https://doi.org/10.55544/jrasb.4.3.4

Keywords:

Phytochemicals, Conventional Antibiotics, Antibiotic-Resistant Bacteria, Synergistic Potential, Antibacterial Mechanisms, Binding Affinities, Therapeutic Applications, Integrated Strategy

Abstract

By the way, this current project is going to demonstrate to us the role of phytochemicals in the fight against antibiotic-resistant bacteria together with the traditional antibiotics. The antibacterial mechanisms of the various phytochemicals from different plants are not limited to just a single one e.g., enzyme inhibition. They also include cell membrane disruption and DNA synthesis inhibition. EGCG, curcumin, and cinnamaldehyde exhibited almost the same effectiveness as the usual antibiotics which become the first step if these compounds are used either individually or in combination with the usual antibiotics. While the conventional antibiotics may be more potent against bacteria, phytochemicals are less toxic and have a reduced chance of resistance insurgence. Based on this review, natural products from plants must be combined with standard treatments in search of enhanced treatment efficacy and, consequently, expanded choices in treatments. The findings have also proved that phytochemicals are effective antimicrobial agents and play a role in a multifaceted approach in the fight against bacterial infection and resistance to antibiotics.

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Published

2025-06-10

How to Cite

Das, S. N., & Mishra, A. K. (2025). Comparing Phytochemicals and Conventional Antibiotics: Mechanisms, Affinities, and Therapeutic Potential Review. Journal for Research in Applied Sciences and Biotechnology, 4(3), 27–34. https://doi.org/10.55544/jrasb.4.3.4

Issue

Vol. 4 No. 3 (2025): June Issue

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Copyright (c) 2025 Dr. Surya Narayan Das, Akshya Kumar Mishra

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